Table 3.
Biomarkers by HIV viral load in plasma.
| Biomarker (log10) | Undetectable (N=91) | Detectable (N=53) | Cohen’s d (p-valuea) |
|---|---|---|---|
| Plasma IFN-γ | 1.83 (0.72), N=57 | 1.58 (0.64), N=24 | 0.36 (0.15) |
| Plasma CXCL10 | 2.59 (0.25), N=71 | 2.99 (0.36), N=28 | −1.38 (<0.001***) |
| Plasma IL-6 | 0.40 (0.58), N=82 | 0.24 (0.45), N=48 | 0.31 (0.09) |
| Plasma TNF-α | 1.08 (0.73), N=81 | 0.85 (0.57), N=46 | 0.34 (0.07) |
| Plasma CCL2 | 1.89 (0.20), N=72 | 1.99 (0.17), N=28 | −0.54 (0.018*) |
| Plasma CXCL8 | 0.53 (0.23), N=89 | 0.60 (0.23), N=53 | −0.30 (0.08) |
| CSF CXCL10 | 2.64 (0.24), N=32 | 3.20 (0.64), N=12 | −1.44 (0.013*) |
| CSF IL-6 | 0.17 (0.16), N=27 | 0.29 (0.19), N=14 | −0.72 (0.036*) |
| CSF TNF-αb | −0.45 (0.22), N=32 | −0.21 (0.38), N=14 | −0.85 (0.045*) |
| CSF CCL2 | 2.54 (0.13), N=29 | 2.53 (0.17), N=12 | 0.10 (0.77) |
| CSF CXCL8 | 1.53 (0.19), N=41 | 1.59 (0.19), N=15 | −0.32 (0.29) |
Values represent means (standard deviations). For biomarkers with missing values, sample size (N) with the available data are given.
a
Notes: Cohen’s d for the difference (undetectable - detectable); P-values are obtained from a two-sample t-test.
b
Negative log10 values reflect the mean raw biomarker values between 0 and 1.
*
P<0.05
**
P<0.01
***
P<0.001