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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Alcohol Clin Exp Res. 2020 Jan 13;44(2):553–566. doi: 10.1111/acer.14269

Figure 5.

Figure 5.

CAPE did not alter ethanol intake in HDID-1 or HDID-2 mice. (A) Schematic timeline for experimental design. (B) 24-hr 2BC intake for each experimental period in HDID-1 and (C) HDID-2 mice. 4-hr intake for mice in the 24-hr 2BC groups for each experimental period in HDID-1 (D) and HDID-2 (E) mice. 4-hr intake for mice in the 2BC DID groups for each experimental period in HDID-1 (F) and HDID-2 (G) mice. H) BALs achieved after 4 hours of ethanol intake for mice in the 2BC and the 2BC DID groups. Baseline = average of Days 9 & 10. Habituation = Days 11-12. Treatment = average of Days 13-17 for 24-hr 2BC (panels B-C) and 13-18 for 4-hr 2BC DID (panels D-G) with drug or vehicle injections each day. Means ± SEM shown for n=15 mice/line/dose/drinking procedure.