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Effects of Ibrutinib on DID ethanol intake on Day 2 each week. A) 6.25 and 25 mg/kg Ibrutinib reduced ethanol intake in female HDID-1 mice. 25 mg/kg Ibrutinib reduced achieved BALs in female HDID-1 mice. B) No effect of Ibrutinib was observed upon re-testing re-randomized groups in week 2. * p<0.05, ** p<0.01. Means ± SEM shown for n=6 mice/sex/treatment dose.
