Table 1.
Significant differential gene expression by RNA sequencing following OFT‐banding.
| Gene symbol/name | Biological function/involvement | Corrected log2 FC | SEM | Corrected P‐value |
|---|---|---|---|---|
| ENS‐1/Embryonic normal stem cell 1 | Developmental regulation | −0.91 | 0.16 | 2.98E‐05 |
| TIMM10/Translocase of inner mitochondrial membrane 10 | Protein transport | 0.72 | 0.13 | 2.98E‐05 |
| ERNI/Early response to neural induction ERNI | Developmental regulation | −0.76 | 0.15 | 4.79E‐04 |
| GBX2/Gastrulation brain homeobox 2 | Transcription factor | 0.83 | 0.17 | 8.27E‐04 |
| LDHB/Lactate dehydrogenase B | Metabolic catalytic activity | 0.64 | 0.13 | 1.23E‐03 |
| TNNC2/Troponin C2, fast skeletal type | Regulation of muscle contraction | 0.75 | 0.16 | 1.34E‐03 |
| PNO1/Partner of NOB1 homolog | RNA binding | 0.59 | 0.13 | 3.62E‐03 |
| PVALB/Parvalbumin | Calcium ion binding/ contractility | 0.7 | 0.17 | 1.91E‐02 |
| ADORA2B/Adenosine A2b receptor | G protein‐coupled adenosine receptor | −0.74 | 0.18 | 2.08E‐02 |
| ITPK1/Inositol‐tetrakisphosphate 1‐kinase | ATP binding kinase | −0.68 | 0.17 | 2.34E‐02 |
| GLRX/Glutaredoxin | Enzyme, antioxidant defence system | −0.71 | 0.18 | 3.33E‐02 |
| PDCD4/Programmed cell death 4 | RNA binding inhibitor | −0.41 | 0.11 | 3.52E‐02 |
| PIAS2/Protein inhibitor of activated STAT 2 | Transcriptional coregulator | −0.36 | 0.1 | 4.37E‐02 |
| MYL10/Myosin, light chain 10, regulatory | Calcium ion binding | 0.67 | 0.18 | 4.37E‐02 |
| TGM2/Transglutaminase 2 | Crosslinks proteins | −0.38 | 0.1 | 4.37E‐02 |
| DNAJC6/DnaJ heat shock protein family (Hsp40) member C6 | Regulate molecular chaperone | −0.48 | 0.13 | 4.40E‐02 |
| RAP1GAP2 ‐ RAP1 GTPase‐activating protein 2 | GTPase activator | −0.57 | 0.15 | 4.46E‐02 |
| MYL1/Myosin, light chain 1 | Calcium ion binding, structural muscle | 0.54 | 0.15 | 4.46E‐02 |
| H1F0/H1 histone family, member 0 | Compacts histones | −0.64 | 0.18 | 4.46E‐02 |
| IFNGR1/Interferon gamma receptor 1 | Cytokine binding | 0.55 | 0.15 | 4.46E‐02 |
| ARFGAP1/ADP ribosylation factor GTPase‐activating protein 1 | GTPase‐activating | −0.47 | 0.13 | 4.46E‐02 |
| S100A11/S100 calcium binding protein A11 | Calcium ion binding/ contractility | 0.52 | 0.14 | 4.46E‐02 |
| LBH/Limb bud and heart development | Modulator of transcription factors | 0.6 | 0.17 | 4.86E‐02 |
| CDH8/Cadherin 8 | Cell adhesion | −0.6 | 0.16 | 4.86E‐02 |
| GSTA4/Glutathione S‐transferase alpha 4‐like | Cellular defence against toxicity | −0.65 | 0.18 | 4.88E‐02 |
| LGALS1/Galectin 1 | Modulates cell‐cell/cell‐matrix interactions | 0.64 | 0.18 | 4.88E‐02 |
| LLPH/LLP homolog, long‐term synaptic facilitation | Transcription machinery binding | 0.58 | 0.16 | 4.97E‐02 |