. 2019 Nov 30;237(2):443–451. doi: 10.1007/s00213-019-05382-1

Table 2.

Reductions in resting state functional connectivity following administration of 2400 mg N-acetylcysteine compared to placebo in the Default Mode (DMN) and Salience networks (SN) in patients with schizophrenia. Node and Montreal Neurological Institute (MNI) coordinates of regions of interest with significant p values (FDR corrected, controlling for multiple comparisons).

Node and MNI coordinate	Network	p FDR	t statistic
Medial prefrontal cortex (1, 55, − 3)–mid frontal gyrus (− 38, 18, 42) Anterior cingulate cortex (0, 22, 35)–frontal pole (26, 52, 8)	DMN	0.04	t (16) = − 4.75
SN	0.01	t (16) = − 5.51

Node and MNI coordinate

Network

p FDR

t statistic

Medial prefrontal cortex (1, 55, − 3)–mid frontal gyrus (− 38, 18, 42)

Anterior cingulate cortex (0, 22, 35)–frontal pole (26, 52, 8)

DMN

0.04

t (16) = − 4.75

0.01

t (16) = − 5.51