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. 2020 Feb 7;11:110. doi: 10.3389/fmicb.2020.00110

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Copyright © 2020 Tkhilaishvili, Wang, Tavanti, Trampuz and Di Luca.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluation of MRSA ATCC43300 biofilm susceptibility to PYO at different time exposures by IMC. Each curve shows the heat produced by viable bacteria present in the biofilm after 24 h (A), 48 h (B), 72 h (C), 120 h (D), 168 h (E) treatment with different phage titers (ranging from 10² to 10⁷ PFU/ml). Graphs on the right represent the magnification of the graphs on the left. Numbers above curves represent PYO titers (in PFU/ml). Circled values represent the MBECP. GC, growth control (dashed line); NC, negative control.