Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 13;10:2512. doi: 10.1038/s41598-020-59214-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Complex structural rearrangements in the patient ALL_402. (a) A circos plot depicting the genome-wide copy number changes in ALL_402. The first (outer) track shows each chromosome and their banding, the second track shows log R ratios from infinium arrays, the third track shows copy number determined by linked-read WGS in 10 Kb bins, and the fourth (innermost) track shows copy number calls using the CNVnator software. Red indicates gain and blue indicates deletion. Expressed fusion genes are highlighted inside of the circos plot, solid lines indicate in-frame and dashed lines indicate out of frame fusion or truncated genes. (b) The derivative chromosomes as outlined using linked-read WGS. The structures of the expressed fusion genes are shown alongside their derivative chromosomes with the direction of transcription indicated by arrows.