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. 2020 Feb 13;11:822. doi: 10.1038/s41467-020-14551-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a t-Stochastic neighbour embedding (t-SNE) plot showing clustering of single cells from four OCM pairs, with tumour and stromal cells mixed 3:1. b Dot plots quantitating the percentage of cells in the stromal and tumour clusters. Line represents the mean (N = 4 biological independent samples i.e. n = 1 for each of the four OCMs). c, d t-SNE plot from a overlaid with XIST expression (c) and 10 sub-populations identified by hierarchical clustering (d). e Heat maps quantitating the percentage of cells from each patient sample in the 10 sub-populations. Source data for panels b and e are provided as a Source Data file.