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. 2020 Feb 13;11:867. doi: 10.1038/s41467-020-14525-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — Viability of the HTT103QP strain (a) and the α-synuclein strain (b) with 5 mM FMN supplemented during chronological aging. Viability is shown as the fraction of PI negative cells (n = 3 ± SD). HTT103QP cells (c) and α-synuclein cells (d) display an increased H₂O₂ tolerance with FMN supplementation. Cells without or with FMN supplement were grown to OD ≈ 0.2 and treated with different concentrations of H₂O₂. Cell growth was monitored using a microplate reader with lag phase time analyzed using the R package growthrates. Results shown are average values ± SD of biological duplicates. The asterisk (*) indicates significant difference (p < 0.05). Source data are provided as a Source Data file.