Table 5.

Multivariable Analysis for Predictors of Being Prescribed Guideline-Adherent Therapy Among Severe Clostridium difficile Infection Cases (n = 3121)*

	Adjusted odds ratio (95% confidence interval)	p value
Age (years)
18–44	Reference
45–64	1.08 (0.86, 1.37)	0.51
≥ 65	1.37 (1.10, 1.71)	0.01
Charlson comorbidity index
0	Reference
1–2	1.19 (0.98, 1.45)	0.08
≥ 3	1.27 (1.04, 1.55)	0.02
Hospital admission†	2.48 (1.90, 3.24)	< 0.001
Inflammatory bowel disease	1.56 (1.13, 2.17)	0.01
Immunosuppressive therapy in prior 12 weeks	1.21 (1.02, 1.42)	0.03

*Excludes patients with unknown duration of treatment, unknown treatment status, or who did not receive treatment

^†Admitted to hospital at time of or within 7 days after stool collection