Table 1.
Characteristics of the study population
| Characteristic | PIP [N = 1,581,897] | No PIP [N = 674,266] | Primary analysis cohort [N = 2,256,163] |
|---|---|---|---|
| Mean age, years (SD) | 74.0 (7.6) | 69.8 (5.8) | 72.1 (7.4) |
| Male sex (%) | 44.6 | 45.5 | 44.8 |
| Number of ADGs (SD) | 9.2 (3.7) | 6.3 (3.4) | 8.3 (3.7) |
| Number of concurrent medications (SD) | 5.0 (3.1) | 2.1 (2.1) | 4.2 (3.1) |
| Mean number of days spent in hospital in the year prior to index or assigned index date (SD) | 3.6 (11.6) | 0.6 (4.8) | 2.7 (10.1) |
| ≥1 ED visits in the 6 months prior to the index or assigned index date (%) | 32.0 | 10.3 | 25.5 |
| Income quintile (%) | |||
| 1–lowest | 20.1 | 16.4 | 19.0 |
| 2 | 20.9 | 19.6 | 20.5 |
| 3 | 19.5 | 19.8 | 19.6 |
| 4 | 19.4 | 20.9 | 19.9 |
| 5–highest | 19.6 | 23.0 | 20.6 |
| Missing | 0.4 | 0.4 | 0.4 |
| Urban place of residencea (%) | 85.1 | 85.2 | 85.1 |
| Number of prescribers in the year prior to the first PIP (SD) | 2.7 (2.1) | 1.9 (1.4) | 2.5 (1.9) |
| MedsCheck in the year prior (%) | 7.6 | 7.5 | 7.6 |
ADG Aggregate Diagnosis Group, ED emergency department, PIP potentially inappropriate prescription, SD standard deviation
a0.11% of the cohort had missing information on place of residence