Table 1.

Study eligibility criteria in PICOS format

PICOS	Inclusion criteria	Exclusion criteria
Population	Adult (aged ≥ 18 years) patients with primary open-angle glaucoma	Other types of glaucoma, including but not limited to:  Primary congenital forms or childhood glaucomas  Secondary glaucomas  Primary angle closure  Secondary angle closure
Intervention/comparators	Medical interventions including screening, observation and diagnosis	Non-medical interventions
Outcomes	Alongside a full treatment cost estimation, studies must include one of the following outcomes:  quality-adjusted life-years  life-years  any natural measurement of effectiveness related to the disease	Projections about clinical or economic outcomes as standalone
Study design	Decision analytic models evaluating:  Cost effectiveness  Cost utility	1. No decision analytic model developed 2. Other types of economic evaluations, including but not limited to:  Cost–benefit  Cost minimization  Budget impact model

PICOS population, intervention, comparators, outcomes and study design