Table 2.
Comparison of Clinical Characteristics Between Sudden Death Cases and Controls in Wake County, North Carolina, Stratified by Age Group and Sex
| Age 18–54 | Age 55–64 | |||||
|---|---|---|---|---|---|---|
| Men | Cases (n = 124) | Controls (n = 1071) | p value* | Cases (n = 130) | Controls (n = 505) | p value* |
| Smoking†, % | 38.7 | 31.5 | 0.1022 | 58.5 | 39.2 | < 0.001 |
| Obesity†‡, % | 47 | 37.5 | 0.062 | 36.0 | 41.4 | 0.305 |
| Hypertension, % | 52.4 | 16.3 | < 0.001 | 65.4 | 38.8 | < 0.001 |
| Dyslipidemia, % | 29.8 | 13.0 | < 0.001 | 49.2 | 27.7 | 0.012 |
| Diabetes mellitus, % | 21.8 | 5.9 | < 0.001 | 34.6 | 15.5 | < 0.001 |
| Coronary artery disease, % | 10.5 | 2.2 | < 0.001 | 22.3 | 8.3 | < 0.001 |
| Heart failure, % | 9.7 | 1.0 | < 0.001 | 15.4 | 3.6 | < 0.001 |
| Chronic kidney disease, % | 7.3 | 1.3 | < 0.001 | 18.5 | 4.0 | < 0.001 |
| Stroke, % | 2.4 | 0.8 | 0.095 | 11.5 | 2.4 | < 0.001 |
| Women | Cases (n = 50) | Controls (n = 1810) | p value* | Cases (n = 67) | Controls (n = 832) | p value* |
| Smoking†, % | 42 | 18.9 | < 0.001 | 41.8 | 29.9 | 0.043 |
| Obesity†‡, %† | 57.9 | 36.0 | 0.006 | 31.6 | 40 | 0.212 |
| Hypertension, % | 58 | 11.1 | < 0.001 | 67.2 | 24.4 | < 0.001 |
| Dyslipidemia, % | 26 | 5.1 | < 0.001 | 47.8 | 16.47 | < 0.001 |
| Diabetes mellitus, % | 34 | 4.3 | < 0.001 | 29.9 | 9.6 | < 0.001 |
| Coronary artery disease, % | 10 | 0.66 | < 0.001 | 11.9 | 1.8 | 0.001 |
| Heart failure, % | 6 | 0.83 | < 0.001 | 23.9 | 1.1 | < 0.001 |
| Chronic kidney disease, % | 8 | 0.88 | < 0.001 | 10.5 | 2.5 | < 0.001 |
| Stroke, % | 6 | 0.72 | < 0.001 | 7.5 | 1.44 | < 0.001 |
*P values from Pearson’s chi-square test comparing frequencies between cases and controls
†For variables with missing values, proportions and p values are calculated using the non-missing data as the denominator
‡Body mass index (BMI) was missing for 36 and 29 cases and 504 and 252 controls, in 18–54 and 55–64 age group respectively