Figure 1.

LINC00460 Is Highly Expressed in CC Cells

(A) The heatmap of CC microarray GEO: GSE41328. (B) LINC00460 expression in CC and normal tissues in TCGA database. (C) Location of LINC00460 detected by RNA-FISH assay; gray represents LINC00460 expression, and red represents nuclei stained by DAPI (×200). (D) The expression of LINC00460 in four CC cell lines and normal cells (the comparison among multiple groups was analyzed by one-way analysis of variance with Tukey’s post hoc test); *p < 0.05 versus human normal colon mucosal epithelial cell NCM-460. NC, negative control; miR-433-3p, microRNA-433-3p; ceRNA, competing endogenous RNA; CC, colon cancer; RNA-FISH, RNA-fluorescence in situ hybridization; lncRNA, long non-coding RNA; TCGA, The Cancer Genome Atlas; DAPI, 4’,6-diamidino-2-phenylindole.