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. 2019 Dec 18;19:1209–1218. doi: 10.1016/j.omtn.2019.12.006

Figure 2.

Figure 2

LINC00460 Promotes the Proliferation and Invasion Abilities of CC Cells In Vitro (×200)

(A) The transfection efficiency of si-LINC00460 in HCT-116 and LOVO cells was determined by qRT-PCR. (B) The viability of HCT-116 and LOVO cells after transfection of si-LINC00460 or si-NC was measured by CCK-8. (C) Colony formation analysis of HCT-116 and LOVO cells after transfection with si-LINC00460 or si-NC. (D) The invasion ability of HCT-116 and LOVO cells after transfection with si-LINC00460 or si-NC was evaluated by Transwell assay (×200). (E) The transfection efficiency of LINC00460 overexpression plasmid in HCT-116 and LOVO cells determined by qRT-PCR. (F) The viability of HCT-116 and LOVO cells after LINC00460 overexpression assessed by CCK-8. (G) Colony formation of HCT-116 and LOVO cells after LINC00460 overexpression. (H) Invasion ability of HV-116 and LOVO cells after LINC00460 overexpression assessed by Transwell assay (×200). The independent parallel experiments were repeated three times; **p < 0.01 versus the si-NC or Lv-NC groups; comparisons between two groups were analyzed using two-tailed independent t test. CC, colon cancer; NC, negative control; CCK-8, cell counting kit-8; miR-433-3p, microRNA-433-3p.