Transplantation of LEF1/hUCB-MSCs Recovered Cardiac Function in MI Rat
(A) Representative images of echocardiography showed successively improved cardiac function in MI, MI + hUCB-MSCs, and MI + LEF1/hUCB-MSCs at 4 weeks postsurgery. (B–E) Four values representing cardiac function (EF in B; FS in C; LVIDd in D; and LVIDs in E) were measured and compared in histograms. Significant improvements were detected in all MI + LEF1/hUCB-MSC groups.*p < 0.05, **p < 0.01; ns, not significant. Error bar: standard error. White bars, Sham; gray bars, MI; striped bars, MI + hUCB-MSCs; black bars, MI + LEF1/UCB-MSCs.