Table 5.
Prognostic characteristics of first primary screen-detected breast cancers by screening result (n = 244)*
| Characteristics | All cancers No. (%) | Screening result† |
||
|---|---|---|---|---|
| MRI and mammography (n = 87) |
Mammography only (n = 12) |
MRI only (n = 145) |
||
| No. (%) | ||||
| Breast cancer type | ||||
| DCIS | 57 (23.4) | 16 (18.4) | 5 (41.7) | 36 (24.8) |
| Invasive | 187 (76.6) | 71 (81.6) | 7 (58.3) | 109 (75.2) |
| Tumor size, cm | ||||
| ≤1.0 | 92 (52.9) | 27 (43.5) | 4 (57.1) | 61 (58.1) |
| 1.1–2.0 | 55 (31.6) | 21 (33.9) | 1 (14.3) | 33 (31.4) |
| >2.0 | 27 (15.5) | 14 (22.6) | 2 (28.6) | 11 (10.5) |
| Missing‡ | 13 | 9 | 0 | 4 |
| Histologic grade | ||||
| 1 | 28 (16.3) | 4 (6.2) | 2 (28.6)§ | 22 (22.0)§ |
| 2 | 83 (48.3) | 31 (47.7) | 4 (57.1) | 48 (48.0) |
| 3 | 61 (35.5) | 30 (46.2) | 1 (14.3) | 30 (30.0) |
| Missing | 15 | 6 | 0 | 9 |
| Lymph nodes | ||||
| Positive | 26 (14.6) | 21 (32.3) | 1 (14.3) | 4 (3.8) |
| Negative | 152 (85.4) | 44 (67.7) | 6 (85.7) | 102 (96.2)§ |
| Missing | 9 | 6 | 0 | 3 |
| Stage at diagnosis | ||||
| I | 139 (80.3) | 41 (67.2) | 5 (71.4) | 93 (88.6)§ |
| II | 31 (17.9) | 17 (27.9) | 2 (28.6) | 12 (11.4) |
| III | 3 (1.7) | 3 (4.9) | 0 (0.0) | 0 (0.0) |
| Missing‡ | 14 | 10 | 0 | 4 |
| Estrogen receptor | ||||
| Positive | 133 (73.9) | 50 (73.5) | 6 (85.7) | 77 (73.3) |
| Negative | 47 (26.1) | 18 (26.5) | 1 (14.3) | 28 (26.7) |
| Missing | 7 | 3 | 0 | 4 |
| Progesterone receptor | ||||
| Positive | 116 (64.4) | 43 (63.2) | 5 (71.4) | 68 (64.8) |
| Negative | 64 (35.6) | 25 (36.8) | 2 (28.6) | 37 (35.2) |
| Missing | 7 | 3 | 0 | 4 |
| HER2 | ||||
| Positive | 18 (10.4) | 10 (15.4) | 0 (0.0) | 8 (7.9) |
| Negative | 155 (89.6) | 55 (84.6) | 7 (100.0) | 93 (92.1) |
| Missing | 14 | 6 | 0 | 8 |
| Triple negative | ||||
| No | 138 (77.1) | 52 (76.5) | 6 (85.7) | 80 (76.9) |
| Yes | 41 (22.9) | 16 (23.5) | 1 (14.3) | 24 (23.1) |
| Missing | 8 | 3 | 0 | 5 |
*
Excludes women with a prior breast cancer (n = 34): MRI and mammography (n = 5); MRI only (n = 24); mammography only (n = 5). DCIS = ductal carcinoma in situ; MRI = magnetic resonance imaging.
†
MRI and mammography refers to an abnormal result both on MRI and mammography; MRI only refers to an abnormal result on MRI only; mammography only refers to an abnormal result on mammography only.
‡
Includes cancers treated with neoadjuvant therapy (n = 8 MRI and mammography; n = 1 MRI only).
§
Compared with MRI and mammography (P < .05).