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. 2020 Jan 16;16(5):815–826. doi: 10.7150/ijbs.37275

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This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

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ITGA1 promotes cell migration in colorectal cancer (CRC) cells in vitro determined by scratch assay. The SW480 and NCM460 were infected with LV-shNC, LV-shITGA1 and LV-ITGA1, LV-NC, respectively. The capability of cell migration was accessed by cell scratch wound healing assay. A and C, representative images of scratch assay of NCM460, SW480 cells infected with indicated viruses, respectively. B and D, relevant quantification of the results of cell migration index (A) and (C), respectively. ITGA1 showed an ability to promote CRC cell migration. Error bars represent mean ± SD. Statistical analysis was performed using Student's t-test. Compared to Lv-NC or LV-shNC infected cells, * and ** represent p<0.05 and p<0.01, respectively (n=3).