Table 1.
Correlation of ITGA1 with clinicopathological features, stages and colorectal neoplasms markers of colorectal cancer
| Group | Number of cases | Concentration μg/mL | t/F value | p value |
|---|---|---|---|---|
| Serum | 39.3/5.93 | |||
| Healthy subjects | 50 | 1.79±0.43 | <0.0001 | |
| CRC patients | 100 | 4.19±1.82 | ||
| Gender | 1.072/1.363 | |||
| Male | 27 | 4.56±1.99 | 0.177 | |
| Female | 73 | 3.60±1.45 | ||
| Age | 0.634/- | |||
| 40-49 | 20 | 4.73±2.44 | 0.596 | |
| 50-59 | 33 | 4.30±1.70 | ||
| 60-69 | 22 | 4.49±1.74 | ||
| 70- | 25 | 3.47±1.55 | ||
| Diagnosis | 1.849/0.903 | |||
| Rectal cancer | 40 | 3.80±1.38 | 0.370 | |
| Colon cancer | 60 | 4.41±2.18 | ||
| TNM staging | 5.56/- | |||
| I + II | 24 | 2.82±0.81 | <0.0001 | |
| III + IV | 76 | 4.71±1.91 | ||
| Duke's staging | 2.5/- | |||
| A | 16 | 3.08±0.81 | 0.067 | |
| B | 19 | 4.03±1.93 | ||
| C | 22 | 3.27±1.19 | ||
| D | 43 | 5.19±2.14 | ||
| CEA | 1.765/1.251 | |||
| Positive | 66 | 4.50±2.04 | 0.215 | |
| Negative | 34 | 3.60±1.25 | ||
| CA125 | 1.215/0.155 | |||
| Positive | 56 | 3.10±1.27 | 0.877 | |
| Negative | 44 | 4.14±1.59 | ||
| CA199 | 4.772/2.339 | |||
| Positive | 67 | 4.76±2.05 | 0.022 | |
| Negative | 33 | 3.10±0.97 | ||
| Tumor metastasis | 1.062/0.980 | |||
| Yes | 55 | 4.49±2.02 | 0.331 | |
| No | 45 | 3.80±1.42 |
Note: Data represented the mean ± SD analyzed by Student's t-test using SPSS. CEA, carcinoembryonic antigen; CA199, carbohydrate antigen 199; CA125, carbohydrate antigen 125; t/F value, the statistical values of the F-test and t-test, respectively.