Figure 1.
Differences in diagnostic sensitivity between integrated and single tumor-associated material detection. The X axis denotes the sensitivity, and the Y axis represents different TAM combination panels. TAM, tumor-associated material. The combination of exosomes and DNA greatly improved cancer detection in 16 sample sizes 39. Compared to single-marker detection in the T7900M locus, the combination of exosomes and ctDNA improved the detection of positive patients from 41 to 44 out of 49. Likewise, for the EGFR activation site, detection was increased from 44 to 53 out of 54 patients 32. Meanwhile, the combined detection of protein and ctDNA also increased the sensitivity from 66 to 141 of 221 patients 7. The sample sizes are as follows.