Figure 4.
Exodisc for PCa EVs isolation. (A) Layout and working principle of Exodisc-B with centrifugal double-filtration system. (B) Heat map of protein types of human-plasma-driven EVs extracted from PCa patients and healthy donors. Measurements sorting along HSP90 expression level for three EV markers (CD81, CD63 and CD9) and five cancer markers (EGFR1, PSMA, PSA, EpCAM and HSP90) measured from lysates of EVs using direct ELISA. Adapted with permission from 83, copyright 2019 Ivyspring International Publisher.