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. 2020 Feb 7;8:59. doi: 10.3389/fbioe.2020.00059

FIGURE 5.

FIGURE 5

Curcuminoids production in E. coli BL21 (DE3) (mono-culture) using caffeic acid (1, 2) and tyrosine (3,4) as substrates, after 63 h of fermentation. Two different pathways were tested with two different enzymes, CCoAOMT (1,3) and COMT (2,4). TAL, tyrosine ammonia lyase; C3H, 4-coumarate 3-hydroxylase; COMT, caffeic acid O-methyltransferase; CCoAOMT, caffeoyl-CoA O-methyltransferase; 4CL, 4-coumarate-CoA ligase; DCS, diketide-CoA synthase; CURS1, curcumin synthase 1.