Table 3. Outcomes and indicators.
AcME-Lao split-plot community-randomized trial, Lao People’s Democratic Republic. (note: HCCA = health center catchment area; FTAT = focal test and treat; MTAT = mass test and treat; RDT = rapid diagnostic test; HS-RDT = high-sensitivity rapid diagnostic test).
| Outcome | Measurement metric |
|---|---|
|
Plasmodium falciparum prevalence in all persons aged
≥18 months |
Prevalence of infection detected by PCR |
|
P. falciparum malaria case incidence among all ages,
matched to village by name |
Cumulative incidence by RDT by routine testing at reporting sites in districts
(health centers, PPM sites, and district hospitals) |
| HS-RDT and RDT test positivity rate | HS-RDT and RDT positivity rate data from village based MTAT-HS |
| Total and confirmed outpatient (OPD)
P. falciparum malaria
case incidence among all ages at the health facility level |
Cumulative incidence by RDT by routine testing at reporting sites in districts
(health centers, PPM sites, and district hospitals) |
| HS-RDT and RDT test positivity rate | HS-RDT and RDT positivity data from FTAT in forest/rice-field based HRPs |
| Cost and cost-effectiveness of interventions. | Cost using standard procedures for costing methods and cost-effectiveness
28
and will be based on a health-sector (provider) perspective. |
| P. falciparum prevalence by each testing methodology | Prevalence of infection detected by PCR, RDT, and HS-RDT |
| P. vivax prevalence in all persons aged ≥18 months | Prevalence of infection detected by PCR |
| Total and confirmed outpatient (OPD)
P. vivax malaria case
incidence among all ages, matched to village by name |
Cumulative incidence by RDT by routine testing at reporting sites in districts
(health centers, PPM sites, and district hospitals) |
| Acceptability and feasibility of MTAT | Proportion of survey respondents who strongly disagree, disagree, are
ambivalent, agree and strongly agree on the importance and acceptability of community-based MTAT |
| Acceptability of FTAT | Proportion of HRP survey respondents who strongly disagree, disagree, are
ambivalent, agree and strongly agree on the importance and acceptability of peer navigator-based FTAT |
| Feasibility of FTAT | Proportion of peer navigators who rate conducting the FTAT intervention as
very easy, somewhat easy, somewhat difficult, and very difficult, and changes in proportions over time |