Figure 1.

One-step growth curves of rabies virus (RABV) in mouse neuroblastoma (NA) cells. NA cells were infected with rHEP-G or rHEP-G-M^min at a multiplicity of infection (MOI) of 0.01 (multi-step) or 3 (one-step) at 37 °C. Culture supernatants were collected at the indicated times and virus titers were assayed in triplicate. Mean data are shown. Asterisks indicate significant differences between the groups calculated using a Student’s t test (* p < 0.05).