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. 2019 Dec 29;9(1):88. doi: 10.3390/jcm9010088

Table 4.

Histological scores in the two treatment groups.

Variable Cryotherapy Control p-Value (Mann-Whitney U)
Fibrosis—intraoperative 0 (1) 0 (2) 0.975
Fibrosis—1st follow-up visit 2 (1) 2 (0) 0.541
Fibrosis—2nd follow-up visit 2 (1) 1 (1) 0.092
Mononuclear (inflammatory) cell infiltrate—intraoperative 3 (1) 3 (1) 0.838
Mononuclear (inflammatory) cell infiltrate—1st follow-up visit 1(1) 1.5 (1) 0.003
Mononuclear (inflammatory) cell infiltrate—2nd follow-up visit 0 (1) 1 (0) 0.000
Edema—intraoperative 2 (0) 2 (1) 0.446
Edema—1st follow-up visit 0.5 (1) 1 (1) 0.000
Edema—2nd follow-up visit 0 (1) 1 (1) 0.040
Ciliated cells—intraoperative 1 (0) 1 (1) 0.091
Ciliated cells—1st follow-up visit 2 (1) 1 (1) 0.007
Ciliated cells—2nd follow-up visit 2 (1) 1 (1) 0.000
Goblet cells—intraoperative 1 (1) 1 (1) 0.055
Goblet cells—1st follow-up visit 0 (1) 1 (1) 0.001
Goblet cells—2nd follow-up visit 0 (0) 1 (1) 0.000
Epithelial hyperplasia—intraoperative 2 (1) 2 (1) 0.273
Epithelial hyperplasia—1st follow-up visit 1 (2) 2 (1) 0.030
Epithelial hyperplasia—2nd follow-up visit 0 (1) 1 (0) 0.001
Squamous metaplasia—intraoperative 1 (1) 1 (1) 0.937
Squamous metaplasia—1st follow-up visit 1 (1) 1 (1) 0.082
Squamous metaplasia—2nd follow-up visit 0 (1) 1 (1) 0.069

1st follow-up visit—3 months following surgery; 2nd follow-up visit—12 months following surgery.