Table 3.
Proportions of Prevalent Patients with Risk Determinants of Pulmonary Arterial Hypertension Mortality in their Low, Intermediate and High Risk Range.
| Risk Determinants | Low Risk | Intermediate Risk | High Risk |
|---|---|---|---|
| WHO FC | 52% | 44% | 4% |
| 6 MWD | 41.7% | 53% | 5.3% |
| BNP/NT-proBNP | 40.6% | 30.8% | 28.6% |
| RAA | 25.7% | 44.8% | 29.5% |
| RAP | 65.9% | 28.7% | 5.4% |
| CI | 57.9% | 22.7% | 19.4% |
The low, intermediate and high risk ranges for the prognostic parameters are as follows: WHO FC I and II, III, IV; 6 MWD >440 m, 165–440 m, <165 m; NT-proBNP <300 ng/L, 300–1400 ng/L, >1400 ng/L; BNP<50 ng/l50–300 ng/L, >300 ng/L; RAA < 18 cm2, 18–26 cm2, >26 cm2; RAP <8 mm Hg, 8–14 mm Hg, >14 mm Hg; CI >2.5 kg/min/m2, 2.0-2.5 kg/min/m2, <2.0 kg/min/m2. CI—cardiac index, WHO FC—World Health Organization Functional Class, NT-proBNP—N-terminal pro-B-type Natriuretic Peptide, 6 MWD—six min walking distance, RAA—right atrial area, RAP—right atrial pressure.