Table 5.
Descriptive statistics for centrality measure about MRI studies on schizophrenia from 2004 to 2018.
| Period | Rank of MeSH terms | High-frequency MeSH terms/MeSH subheadings | Centrality | Rank of MeSH terms | High-frequency MeSH terms/MeSH subheadings | Centrality | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Degree | Betweenness | Closeness | Degree | Betweenness | Closeness | |||||
| 2004–2008 | 3 | Magnetic Resonance Imaging | 674.000 | 5.320 | 89.286 | 15 | Antipsychotic Agents/therapeutic use | 99.000 | 3.174 | 80.645 |
| 1 | Schizophrenia/physiopathology | 663.000 | 8.417 | 100.000 | 16 | Cerebral Cortex/pathology | 93.000 | 2.587 | 75.758 | |
| 4 | Schizophrenia/diagnosis | 461.000 | 8.417 | 100.000 | 14 | Brain Mapping | 91.000 | 1.650 | 71.429 | |
| 5 | Schizophrenic Psychology | 429.000 | 5.313 | 92.593 | 21 | Diffusion Magnetic Resonance Imaging | 86.000 | 1.927 | 71.429 | |
| 2 | Schizophrenia/pathology | 415.000 | 7.593 | 96.154 | 20 | Brain/anatomy & histology | 81.000 | 1.653 | 73.529 | |
| 7 | Image Processing, Computer-Assisted | 389.000 | 1.736 | 78.125 | 24 | Image Interpretation, Computer-Assisted/methods | 72.000 | 0.482 | 62.500 | |
| 6 | Brain/pathology | 299.000 | 3.682 | 80.645 | 25 | Temporal Lobe/pathology | 69.000 | 2.238 | 73.529 | |
| 8 | Brain/physiopathology | 275.000 | 5.543 | 86.207 | 11 | Schizophrenia/complications | 69.000 | 1.530 | 71.429 | |
| 9 | Schizophrenia/genetics | 178.000 | 7.441 | 96.154 | 23 | Cerebral Cortex/physiopathology | 67.000 | 1.454 | 71.429 | |
| 17 | Imaging, Three-Dimensional | 162.000 | 1.246 | 73.529 | 19 | Magnetic Resonance Imaging/statistics & numerical data | 65.000 | 1.313 | 71.429 | |
| 12 | Prefrontal Cortex/physiopathology | 144.000 | 3.388 | 80.645 | 26 | Prefrontal Cortex/pathology | 63.000 | 1.480 | 75.758 | |
| 10 | Magnetic Resonance Imaging/methods | 135.000 | 4.448 | 83.333 | 22 | Schizophrenia/epidemiology | 55.000 | 2.312 | 73.529 | |
| 13 | Schizophrenia/drug therapy | 121.000 | 2.806 | 80.645 | 18 | Schizophrenia/metabolism | 41.000 | 0.851 | 67.568 | |
| 2009– 2013 | 1 | Schizophrenia/pathology | 1322.000 | 10.606 | 100.000 | 16 | Psychotic Disorders/pathology | 140.000 | 4.133 | 80.488 |
| 2 | Schizophrenia/physiopathology | 909.000 | 9.658 | 97.059 | 27 | Neural Pathways/pathology | 127.000 | 4.210 | 80.488 | |
| 4 | Schizophrenic Psychology | 754.000 | 10.606 | 100.000 | 22 | Temporal Lobe/pathology | 114.000 | 3.411 | 78.571 | |
| 3 | Brain/pathology | 700.000 | 7.333 | 91.667 | 25 | Neural Pathways/physiopathology | 114.000 | 2.137 | 71.739 | |
| 5 | Brain/physiopathology | 488.000 | 5.934 | 84.615 | 23 | Bipolar Disorder/pathology | 114.000 | 1.953 | 71.739 | |
| 7 | Magnetic Resonance Imaging | 447.000 | 8.232 | 91.667 | 28 | Cognition Disorders/etiology | 113.000 | 2.103 | 71.739 | |
| 6 | Brain Mapping | 397.000 | 8.011 | 91.667 | 21 | Cerebral Cortex/physiopathology | 111.000 | 2.063 | 71.739 | |
| 10 | Schizophrenia/complications | 320.000 | 6.084 | 84.615 | 26 | Brain/blood supply | 111.000 | 0.794 | 67.347 | |
| 9 | Magnetic Resonance Imaging/methods | 302.000 | 6.204 | 84.615 | 20 | Hippocampus/pathology | 104.000 | 3.953 | 78.571 | |
| 8 | Schizophrenia/genetics | 281.000 | 9.526 | 97.059 | 29 | Emotions/physiology | 102.000 | 1.975 | 71.739 | |
| 12 | Schizophrenia/diagnosis | 246.000 | 7.139 | 89.189 | 34 | Image Interpretation, Computer-Assisted/methods | 100.000 | 1.012 | 67.347 | |
| 11 | Cerebral Cortex/pathology | 244.000 | 4.293 | 82.500 | 30 | Brain Mapping/methods | 98.000 | 2.873 | 75.000 | |
| 19 | Image Processing, Computer-Assisted | 204.000 | 3.886 | 78.571 | 24 | Prefrontal Cortex/pathology | 94.000 | 0.607 | 66.000 | |
| 13 | Nerve Fibers, Myelinated/pathology | 200.000 | 5.405 | 84.615 | 15 | Schizophrenia/drug therapy | 91.000 | 2.404 | 75.000 | |
| 17 | Nerve Net/physiopathology | 172.000 | 1.468 | 70.213 | 31 | Frontal Lobe/pathology | 86.000 | 3.229 | 76.744 | |
| 14 | Prefrontal Cortex/physiopathology | 155.000 | 2.383 | 71.739 | 33 | Diffusion Tensor Imaging/methods | 85.000 | 0.917 | 68.750 | |
| 18 | Memory, Short-Term/physiology | 148.000 | 4.309 | 78.571 | 32 | Antipsychotic Agents/therapeutic use | 73.000 | 1.154 | 70.213 | |
| 2014- 2018 | 1 | Schizophrenia/physiopathology | 1240.000 | 7.924 | 97.222 | 13 | Schizophrenia/complications | 166.000 | 7.320 | 89.744 |
| 2 | Schizophrenia/pathology | 945.000 | 8.434 | 97.222 | 21 | Cerebral Cortex/pathology | 155.000 | 4.272 | 79.545 | |
| 4 | Brain/physiopathology | 577.000 | 3.869 | 83.333 | 16 | Schizophrenia/drug therapy | 154.000 | 3.862 | 81.395 | |
| 3 | Schizophrenia/diagnostic imaging | 514.000 | 7.642 | 94.595 | 24 | Bipolar Disorder/pathology | 131.000 | 0.889 | 64.815 | |
| 5 | Schizophrenic Psychology | 466.000 | 7.722 | 94.595 | 23 | Brain Mapping/methods | 129.000 | 4.990 | 83.333 | |
| 6 | Brain/pathology | 407.000 | 5.881 | 85.366 | 17 | Schizophrenia/diagnosis | 126.000 | 5.120 | 83.333 | |
| 7 | Magnetic Resonance Imaging/methods | 360.000 | 9.382 | 97.222 | 34 | Bipolar Disorder/physiopathology | 117.000 | 1.391 | 70.000 | |
| 9 | Brain/diagnostic imaging | 279.000 | 2.225 | 76.087 | 27 | Memory, Short-Term/physiology | 113.000 | 1.535 | 71.429 | |
| 10 | White Matter/pathology | 262.000 | 5.741 | 87.500 | 25 | Brain Mapping | 111.000 | 4.194 | 79.545 | |
| 14 | Nerve Net/physiopathology | 240.000 | 4.592 | 83.333 | 30 | Psychotic Disorders/diagnostic imaging | 111.000 | 3.946 | 81.395 | |
| 15 | Psychotic Disorders/physiopathology | 237.000 | 5.823 | 89.744 | 28 | White Matter/diagnostic imaging | 108.000 | 2.059 | 72.917 | |
| 8 | Schizophrenia/genetics | 213.000 | 7.621 | 92.105 | 29 | Diffusion Tensor Imaging/methods | 107.000 | 4.112 | 74.468 | |
| 11 | Magnetic Resonance Imaging | 205.000 | 7.086 | 89.744 | 26 | Antipsychotic Agents/therapeutic use | 101.000 | 2.463 | 72.917 | |
| 12 | Prefrontal Cortex/physiopathology | 198.000 | 2.618 | 76.087 | 32 | Neural Pathways/physiopathology | 99.000 | 1.663 | 72.917 | |
| 19 | Connectome/methods | 194.000 | 3.040 | 79.545 | 31 | Emotions/physiology | 93.000 | 2.463 | 76.087 | |
| 18 | Cerebral Cortex/physiopathology | 182.000 | 2.482 | 77.778 | 35 | Prefrontal Cortex/pathology | 88.000 | 3.268 | 76.087 | |
| 22 | Psychotic Disorders/pathology | 176.000 | 2.386 | 72.917 | 33 | Hippocampus/pathology | 78.000 | 1.446 | 70.000 | |
| 20 | Gray Matter/pathology | 168.000 | 4.280 | 79.545 | 36 | Schizophrenia/metabolism | 48.000 | 1.257 | 68.627 | |