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. 2020 Jan 7;12(1):164. doi: 10.3390/nu12010164

Figure 4.

Figure 4

HAE ameliorated oxidative stress by upregulating the phase II enzyme pathway in mice livers and hearts. Con, control; P407, poloxamer 407; P407 + HAE, poloxamer 407 plus HAE at 200 mg/kg/day. (A) Liver protein carbonyl content (left, western blot image; right, statistical analysis). (B) Liver SOD, GST, GPX, and γ-GCS activities. (C) The liver GSH/GSSG ratio. (D) Heart protein carbonyl content (left, western blot image; right, statistical analysis). (E) Heart SOD, GST, GPX, and γ-GCS activities. (F) The heart GSH/GSSG ratio. (G) Liver Nrf2, NQO1, HO1, and MnSOD protein expression (left, western blot image; right, statistical analysis). (H) Heart Nrf2, NQO1, HO1, and MnSOD protein expression (left, western blot image; right, statistical analysis). The values are the means ± S.E.M. (n = 8); * p < 0.05; ** p < 0.01.