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. 2020 Jan 8;9(1):176. doi: 10.3390/jcm9010176

Table 2.

Hazard ratio of serum uric acid for major adverse renal event with Cox proportional hazard models by sex.

Total Subjects Male Female
HR [95% CI] p-Value HR [95% CI] p-Value HR [95% CI] p-Value
Crude 1.376 [1.329; 1.425] <0.001 1.346 [1.283; 1.413] <0.001 1.514 [1.427; 1.606] <0.001
Model 1 1.398 [1.343; 1.447] <0.001 1.338 [1.274; 1.404] <0.001 1.507 [1.419; 1.600] <0.001
Model 2 1.288 [1.227; 1.352] <0.001 1.211 [1.134; 1.293] <0.001 1.415 [1.316; 1.522] <0.001
Model 3 1.260 [1.191; 1.332] <0.001 1.188 [1.104; 1.279] <0.001 1.381 [1.259; 1.513] <0.001

Model 1, crude + age, sex (exclude sex in subgroup analysis). Model 2, Model 1 + creatinine, diastolic blood pressure. Model 3, Model 2 + anemia, body mass index, cholesterol, diabetes mellitus. Abbreviation: CI, confidence interval; HR, hazard ratio.