Table 1.
Comparison of the selected risk factors and biochemical parameters obtained in subjects with stroke in both etiological subgroups of cerebral ischemia.
| Parameter | LAA N = 20 | SVD N = 49 | p Values |
|---|---|---|---|
| Age median (range) * | 67 (45–85) | 68 (40–89) | 0.7761 |
| Sex, male, N (%) ** | 14 (70%) | 21 (42.9%) | 0.0408 |
| Hypertension, N (%) ** | 17 (85%) | 44 (89.7%) | 0.6822 |
| Diabetes, N (%) ** | 8 (40%) | 17 (34.7%) | 0.7842 |
| Hyperlipidemia, N (%) ** | 10 (50%) | 18 (36.7%) | 0.4185 |
| Smoking, N (%) ** | 11 (55%) | 13 (26.5%) | 0.0299 |
| Ischemic heart disease, N (%) ** | 3 (15.0%) | 6 (12.2%) | 0.7120 |
| CRP (mg/L) median (range) * | 4.90 (0.43–30.45) | 4,79 (0.36–29.15) | 0.7660 |
| HbA1c (%) median (range) * | 5.9 (5.2–10.04) | 5.6 (5.0–9.8) | 0.2313 |
| Homocystein (µmolµ/L) median (range) * | 10.67 (5.1–30.92) | 10.87 (3.52–48.6) | 0.6153 |
| Fibrinogen (mg/dL) median (range) * | 312.5 (234–590) | 300 (369–540) | 0.2992 |
| Obesity, N (%) ** | 12 (60%) | 36 (73.47%) | 0.2699 |
| The volume of ischemic focus DWI (cm3) median (range) * | 2.23 (0.12–10.3) | 0.89 (0.09–1.5) | 0.0694 |
| The volume of ischemic focus FLAIR (cm3) Median (range) * | 3.46 (0.35–31.8) | 0.99 (0.18–1.71) | 0.0846 |
| Platelet reactivity: optical aggregometry (AUC) median (range) * | 17.1 (0–208.6) | 20.4 (0–154.2) | 0.7147 |
| Platelet reactivity: impedance aggregometry (AUC) median (range) * | 42 (9–101) | 27.5 (6–108) | 0.0622 |
| Resistance to ASA (multiplate), % ** | 52.3% | 22.9% | 0.0286 |
* U Mann-Whitney test; ** chi square test. Note: FLAIR = fluid-attenuated inversion recovery; ASA = acetylsalicylic acid; AUC = area under the curve; DWI- diffusion-weighted imaging; CRP = C-reactive protein; HbA1c- glycated hemoglobin; LAA = large artery atherosclerosis; SVD = small-vessel disease; N = number of subjects, bold font = statistically significant p Values.