Table 1.

Immunotherapeutic potential of ex vivo-educated dendritic cells (DCs).

Desired Trait	PGE2 DC	Type 1-polarized DC	References
Antigen Presentation	++++	++++++	[52]
Maturation status (high CD83 / CD86)	++++++	++++++	[62,64]
Lymph node homing (CCR7)	++++++	++++	[60,61,62,63,64]
IL-12p70, IL-15 production	Deficient	++++++++	[62,64,72]
T cell trafficking / chemokine expression	CCL22 (TREG)	CCL19 (TN, TCM)	[63,69,73,74]
		CCL3-5, CXCL9-11 (TEM)
Antigen transfer ability	Deficient	++++++	[64]