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Anti-E2 IgG1 and IgG3 responses were examined at the peak HCV RNA time point and at the initial decline in viral load for both clearer and chronic progressor subjects. Anti-E2 IgG subclass responses at the peak HCV RNA time points were compared for anti-E2 IgG1 (A) or anti-E2 IgG3 (B). Additionally, time points where initial HCV RNA decline occurred were compared for clearers and chronic progressors for anti-E2 IgG1 (C) and anti-E2 IgG3 (D) responses.
