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. 2019 Dec 24;11(1):21. doi: 10.3390/mi11010021

Figure 4.

Figure 4

In vitro BBB-integrated neurovascular unit models. (a) Horizontal-aligned microfluidic neurovascular unit model with neuron, astrocyte, and endothelium. Reproduced with permission from [81]. Copyright 2017, The Royal Society of Chemistry (RSC). (b) Vertical-aligned neurovascular unit consisting neuron, astrocyte, pericyte, and endothelium with Ag/AgCl TEER electrodes. Reproduced with permission from [84]. Copyright 2016, ACS publication. (c) Horizontal-aligned neurovascular unit model with neural stem cells (NSCs) and endothelium for induction of crosstalk between NSC and endothelium. Reproduced with permission from [87]. Copyright 2014, WILEY-VCH.