Table 1.
Clinical and demographic characteristics of the patients included in the study.
| All Patients Included in the Study | Oliguric/Anuric Group | Normal Urinary Output Group | p Value * | |
|---|---|---|---|---|
| Number of patients N | 71 | 19 | 52 | |
| Age Mean ± SD | 62.6 ± 14.7 | 61.4 ± 10.7 | 62.9 ± 15.1 | 0.57 |
| Weight (actual) kg Mean ± SD | 82.5 ± 20.0 | 88.5 ± 21.4 | 79.9 ± 19.6 | 0.14 |
| Body Surface Area Mean ± SD | 1.9 ± 0.2 | 2.0 ± 0.2 | 1.9 ± 0.2 | 0.09 |
| Diagnosis N (%) | ||||
| Sepsis | 37 (52.1) | 13 (68.4) | 21 (40.4) | 0.03 |
| Septic shock | 34 (47.9) | 6 (31.6) | 31 (59.6) | 0.03 |
| Type of sepsis N (%) | N (%) | |||
| Medical | 26 (36.6) | 8 (42.1) | 19 (36.5) | 0.66 |
| Surgical | 45 (63.4) | 11 (57.9) | 33 (63.5) | 0.66 |
| Ventilation N (%) | N (%) | |||
| Mechanically ventilated | 49 (69) | 18 (94.7) | 31 (59.6) | 0.04 |
| Spontaneous ventilation | 22 (31) | 1 (5.3) | 21 (40.4) | 0.04 |
| PEEP for Mechanically ventilated at study inclusion (T0) Mean ± SD | 5.7 ± 1.1 | 6 ± 1.2 | 5.5 ± 0.9 | 0.16 |
| SOFA Score at study inclusion (T0) Mean ± SD points | 9.5 ± 3.2 | 11.3 ± 2.9 | 8.8 ± 3.2 | 0.02 |
| SOFA Score without renal SOFA at study inclusion (T0) Mean ± SD points | 7.1 ± 2.5 | 8.2 ± 2.2 | 6.8 ± 2.6 | 0.06 |
| Cardiovascular SOFA at study inclusion (T0) Mean ± SD points | 2.8 ± 1.4 | 3.4 ± 1.2 | 2.5 ± 1.3 | 0.03 |
| APACHE II Score at study inclusion (T0) Mean ± SD points | 21.9 ± 8.6 | 23.3 ± 8.5 | 20.8 ± 8.4 | 0.17 |
| Heart Rate at study inclusion (T0) Mean ± SD beats/min | 105.0 ± 20.6 | 108.5 ± 19.2 | 101.6 ± 18.0 | 0.15 |
| Mean arterial blood pressure (MAP) at study inclusion (T0) Mean ± SD mm Hg | 75.2 ± 13.6 | 74.3 ± 16.4 | 75.8 ± 12.8 | 0.68 |
| Lactate at study inclusion (T0) Mean ± SD mmol/l | 2.52 ± 2.2 | 4.1 ± 2.0 | 3.5±2.3 | 0.12 |
| Norepinephrine at study inclusion (T0) Mean ± SD mcg/kg/min | 0.09 ± 0.1 | 0.18 ± 0.1 | 0.06 ± 0.07 | 0.001 |
| VDI Mean ± SD at study inclusion (T0) | 0.14 ± 0.2 | 0.26 ± 0.27 | 0.08 ± 0.1 | 0.001 |
| Creatinine Mean ± SD at study inclusion (T0) µmol/l | 218.3 ± 192.7 | 291.7 ± 226.3 | 192.76 ± 179.5 | 0.06 |
| Urea Mean ± SD at study inclusion (T0) mmol/l | 16.4 ± 12.0 | 20.3 ± 13.7 | 14.6 ± 11.2 | 0.09 |
* p value between the oliguric/anuric group and the normal urinary output group.