Table 2.
Regions of statistically significant reduced gray matter volume (GMV) in early PD compared to healthy control group.
| Region | MNI Coordinates | Voxel Size | GMV, mm3 | t-Value | |
|---|---|---|---|---|---|
| X, Y, Z | PD Group | NC Group | |||
| Superior temporal gyrus, L | −42, 18, −28 | 890 | 399.64 ± 55.33 | 484.67 ± 68.41 | 4.83 |
| Uncus, R | 34, −4, −40 | 461 | 420.08 ± 53.75 | 501.25 ± 57.93 | 4.27 |
| Inferior temporal gyrus, L | −34, −16, −34 | 188 | 446.43 ± 64.39 | 525.71 ± 49.64 | 4.07 |
GMV = grey matter volume, PD = Parkinson’s disease, L = left, R = right, MNI = Montreal Neurological Institute. The statistical criteria were set at joint voxel height uncorrected p < 0.001 and a cluster extent threshold of the family-wise error rate (PFWE) < 0.05.