Table 4.

Association between changes over time in (body composition and metabolic parameters) and changes in gut microbiota abundance in the synbiotic and placebo groups (both groups combined). BMI, Body Mass Index; WC, Waist Circumference; HbA1C, glycated hemoglobin. Data were generated by applying analysis of variance to a mixed linear model, built with the abundance of a given microbe as the response variable, and body composition, metabolic parameter, treatment groups and time points as the predictor variables, with subject number as random variable.

Parameters	Change	Gut Microbiota	Change	p
HbA1C%	$\downarrow$ 5.85%	Lactobacillus	$\uparrow$ 24.1-fold	0.044
Body mass (kg)	$\downarrow$ 7.86%	Bifidobacterium	$\uparrow$ 263.8-fold	0.052
BMI (kg/m2)	$\downarrow$ 7.98%	Bifidobacterium	$\uparrow$ 263.8-fold	0.009
WC (cm)	$\downarrow$ 5.90%	Bifidobacterium	$\uparrow$ 263.8-fold	0.023
Body Fat Mass (kg)	$\downarrow$ 7.89%	Bifidobacterium	$\uparrow$ 263.8-fold	0.011