Table 1.
New classification of the phases of HBV infection.
|
Positive HBeAg
Chronic Infection Chronic Hepatitis |
Negative HBeAg
Chronic Infection Chronic Hepatitis |
Occult HBV Infection | |||
|---|---|---|---|---|---|
| HBsAg | High | High/Intermediate | Low | Intermediate | Negative |
| HBV DNA1 | ≥107 IU/mL | 104–107 IU/mL | <2000 IU/mL | >2000 IU/mL | Positive |
| ALT/AST | Normal | Elevated | Normal | Elevated | Normal |
| Liver disease | None/Minimal | Moderate/Severe | None | Moderate/Severe | Variable |
| Old terminology | Immune tolerant | Immune reactive HBeAg positive | Inactive carrier | HBeAg negative chronic hepatitis | / |
1 HBV DNA in blood HBsAg: Hepatitis B surface Antigen; HBeAg: soluble antigen “e”; HBV DNA: Hepatitis B desoxyribonucleic acide; ALT: alanine-aminotransferase; AST: aspartate-aminotransferase; IU: International Units.