Table 3.
Univariate analyses of factors linked to walking speed (WS) decline (<0.8 m/s).
| Variables | WS ≥ 0.8 m/s (n = 339) |
WS < 0.8 m/s (n = 17) |
p-Value |
|---|---|---|---|
| Age (years) | 65 (29, 94) | 71 (25, 83) | 0.0278 |
| Gender, male/female | 155/184 | 10/7 | 0.3265 |
| HBV/HCV/HBV and HCV/NBNC | 60/170/9/100 | 1/11/0/5 | 0.4852 |
| Body mass index (kg/m2) | 22.7 (14.6, 41.4) | 21.5 (17.7, 29.2) | 0.3367 |
| Presence of LC, yes/no | 125/214 | 12/5 | 0.0088 |
| Total bilirubin (mg/dL) | 0.8 (0.2, 5.1) | 0.9 (0.4, 3.2) | 0.7231 |
| Serum albumin (g/dL) | 4.3 (2.0, 5.2) | 4.0 (2.4, 4.6) | 0.0246 |
| Prothrombin time (%) | 91.4 (11.9, 122.9) | 84.7 (46.5, 103.9) | 0.1597 |
| Platelet count (×104/mm3) | 17.7 (1.4, 51.4) | 16.0 (2.8, 32.2) | 0.1401 |
| AST | 25 (12, 222) | 27 (10, 191) | 0.5570 |
| ALT | 19 (5, 206) | 16 (5, 232) | 0.2200 |
| M2BPGi | 1.24 (0.21, 11.93) | 2.31 (1.08, 10.82) | 0.0141 |
| eGFR (ml/min/1.73m2) | 81 (5, 173) | 76 (7, 99) | 0.0931 |
| HbA1c (NGSP) | 5.7 (3.7, 12.6) | 5.7 (4.6, 7.2) | 0.3573 |
| Serum ammonia (μg/dL) | 38 (12, 195) | 48 (18, 206) | 0.0534 |
| BTR | 5.71 (1.93, 13.82) | 3.92 (1.69, 8.8) | 0.0127 |
| Serum zinc (μg/dL) | 73.9 (22.0, 124.6) | 68.4 (38.0, 94.4) | 0.0764 |
| ECW to TBW ratio | 0.389 (0.367, 0.425) | 0.398 (0.387, 0.421) | <0.0001 |
| SMI decline, yes/no/unknown | 114/223/2 | 7/10/0 | 0.6024 |
Continuous data are expressed as median (range). HCV, hepatitis C virus; HBV, hepatitis B virus; NBNC, non-B and non-C; LC, liver cirrhosis; AST, aspartate aminotransferase; ALT, alanine aminotransferase; M2BPGi, Mac-2 binding protein glycosylation isomer; eGFR, estimated glomerular filtration rate; NGSP, National Glycohemoglobin Standardization Program; BTR, branched-chain amino acid to tyrosine ratio; ECW, extracellular water; TBW, total body water; SMI, skeletal muscle index.