Table 1.
Some clinical data (mean ± standard deviation; median, 25th and 75th percentiles) extracted from medical records of patients at the time of UIC (urinary iodine concentration) evaluation.
| Genoa District n = 229 |
Savona District n = 162 |
Other Districts (1) n = 24 |
Significance p |
|
|---|---|---|---|---|
| Age (years) | 56.8 ± 15.2 | 56.2 ± 17.1 | 54.9 ± 14.5 | 0.83 |
| Gender (female/male) | 179/50 | 118/44 | 19/5 | 0.48 |
| Clinical Diagnosis (%) | <0.0001 (a) | |||
| nodular goiter | 15 | 38 | 17 | |
| Graves’ disease | 10 | 17 | 8 | |
| Hashimoto’s thyroiditis | 8 | 13 | 0 | |
| thyroid cancer | 51 | 18 | 58 | |
| others | 16 | 14 | 17 | |
| Thyroid drugs (%) | <0.0001 (a) | |||
| levothyroxine | 60 | 33 | 63 | |
| methimazole | 13 | 28 | 8 | |
| none | 27 | 39 | 29 | |
| f-T4, free thyroxine (pmol/L) | 16.3 ± 7.5 16.6; 12.7–20.1 |
14.3 ± 5.3 13.4; 10.6–17.0 |
16.2 ± 6.6 14.2; 12.5–20.9 |
0.0003 (b) |
| TSH, thyrotropin (mIU/L) | 7.4 ± 19.4 1.0; 0.2–2.9 |
5.3 ± 16.3 1.2: 0.2–2.9 |
10.7 ± 26.1 1.1; 0.3–5.2 |
0.80 |
| Thyroid peroxidase antibody (% of positivity) | 45 | 44 | 37 | 0.92 |
(1) The other two provinces of the Liguria region (Imperia in the west and La Spezia in the east) and the southern provinces (Cuneo and Alessandria) of the Piedmont region. (a) Χ2 evaluated only between the Genoa and Savona districts; (b) Dunn’s multiple comparison test: Genoa district vs. Savona district p = 0.002.