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. 2020 Jan 10;9(1):188. doi: 10.3390/jcm9010188

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Longitudinal follow-up of the CTC counts for monitoring the disease status of patients with HCC (part I). (A–C) The blood samples were longitudinally collected from patients #1 (panel A), #17 (panel B), and #19 (panel C), who had a high initial serum AFP level followed by a decrease. Series testing of the CTC count and the serum AFP level were performed and plotted accordingly. The disease status (SD, PR, and PD) was determined and was used as an indicator of the patient’s clinical outcome.