Figure 1.
Impact of nutrition in PAH. Dietary components such as Fe2+, vitamins C and D, flavonoids and other related polyphenols, and fiber as well as vitamin D obtained from the exposure to sunlight may have a positive impact the quality of life and prognosis of PAH patients. Each dietary factor may have its own mechanism of action. However, part of the effects of these nutrients may be related to their effect on the immune system with restoration of T cells and cytokines, changes in the microbiota and their bacterial products, and bacterial translocation.