Figure 4.

Silk peptide prevents the development of diet-induced obesity in HFD-induced obese mice. (A) Weekly body mass measurements, (B) body mass gain, and (C) photographs of representative mice treated for 6 weeks. (D) Effect of SP on organ mass in the CD and HFD groups. * p < 0.05 and ** p < 0.01 indicates significantly difference from CD group. (E) Food intake and (F) water consumption per unit body mass. Serum (G) creatinine and (H) leptin concentrations were measured using colorimetric kits. Data are expressed as mean ± SD (n = 8). Values with different letters were significantly different; p < 0.05 (a > ab > b > c).