Table 2.
Proportion of children with sickle cell anemia (SCA) aged 5–12 years old in Nigeria (SPRING cohort; n = 799) with abnormal transcranial Doppler (TCD) values (>200 cm/s): World Health Organization (WHO) compared to the SCA-Specific growth reference.
| Malnutrition | Abnormal TCD, % | p-Value # |
|---|---|---|
| SCA-Specific Growth Reference n = 799 | ||
| No malnutrition | 14.0 | 0.034 |
| Moderate malnutrition | 7.1 | |
| Severe malnutrition | 4.4 | |
| 2007 WHO Growth Reference n = 799 | ||
| No malnutrition | 14.8 | 0.059 |
| Moderate malnutrition | 12.3 | |
| Severe malnutrition | 7.9 | |
Abnormal TCD, >200 cm/s; moderate malnutrition, BMI Z-score <−2 and >−3; severe malnutrition, BMI Z-score <−3. # Chi-square. A p-Value < 0.05 was set for statistical significance.