Fig. 1.

Reduced Tor gene dosage rescues Adar^5G1 mutant phenotypes. Tor mutations increase a viability at eclosion from the pupae, n = 3; b open field locomotion, n > 8; and c lifespan in Adar^5G1mutant flies. FM7 is a first chromosome balancer strain. n = 3. d Immunoblot with antibody to Drosophila Tor protein of Adar^5G1mutant and wild-type (w¹¹¹⁸) fly head protein extracts. n = 3. Quantitation of immunoblot data shows increased level of Tor in Adar^5G1. p values in a and b were calculated by a one-way ANOVA followed by Tukey’s test. The significance of differences between variables was described based on p values: *p value < 0.05, **p value < 0.005, ***p value < 0.001, and n.s (not significant). Error bars: SEM (standard error of mean for biological replicates). p values in d were calculated by Student’s t test. Source data values are included in Additional file 6