Table 3.
The comparison of the serum biochemical markers between case and control groups
| Biochemical factors | Case (Mean ± SE) | Control (Mean ± SE) | Pvaluea | P valueb | OR(95%CI) |
|---|---|---|---|---|---|
| Folate (ng/ml) | 5.8 ± 0.3 | 7.7 ± 0.28 | <0.001 | <0.001 | 0.54 (0.38–0.75) |
| Vitamin B12(pg/ml) | 550.9 ± 55.1 | 954.9 ± 57.7 | <0.001 | <0.001 | 0.996 (0.993–0.998) |
| Hcy1 (μmol/l) | 11.2 ± 1.1 | 11.9 ± 0.9 | 0.2 | 0.5 | 0.97 (0.9–1.05) |
| Trp2(μmol/l) | 70.3 ± 2.9 | 75.3 ± 3.9 | 0.3 | 0.1 | 0.97 (0.94–1.01) |
| Tryptophan/competing amino acids3 | 0.113 ± 0.003 | 0.104 ± 0.002 | 0.02 | 0.5 | 1.46 (0.45–4.76) |
a T- test for Square, square root or logarithm
b Multiple logistic regression after adjusting for job, education, marital status, children number, smoking and hookah use, depression history, unemployment history in the past 5 year, tragic events in the past 6 months and the whole lifetime, energy intake, physical activity and dietary patterns
1 Homocystein
2 Tryptophan
3 Valine, leucine, tyrosine, phenylalanine and isoleucine (These amino acids compete for the same cerebral uptake mechanism)