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MiR-135a downregulated LATS2 by directly targeting the LATS2 3′ UTR. a Predicted miR-135a target sequences in the 3′UTR of LATS2 (LATS2-3′UTR). b Luciferase assays of fibroblasts transfected with LATS2-3′UTR. c Western blot of LATS2 expression after miR-135a overexpression or inhibition in fibroblasts. d Histogram summarizing the results in (c) (n = 3). e Relative LATS2 mRNA expression after miR-135a overexpression or inhibition in fibroblasts (n = 3)
