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. 2020 Feb 13;20:120. doi: 10.1186/s12885-020-6612-2

Table 2.

Treatment and patient outcomes

All patients
(n = 68)
Low sPD-L1
(n = 36)
High sPD-L1
(n = 32)
n (%) n (%) n (%) P
HD-MTX chemotherapy
 Completed 61 (90) 32 (89) 29 (91) >  0.999
 Failed to complete 7 (10) 4 (11) 3 (9)
Response to HD-MTX treatment
 CR/PR 54/12 (97) 30/6 (100) 24/6 (94) 0.486
 SD/PD 1/1 (3) 0/0 (0) 1/1 (6)
Intrathecal chemotherapy
 Combined 26 (38) 10 (28) 16 (50) 0.081
 Not combined 42 (62) 26 (72) 16 (50)
Whole brain radiotherapy
 Done 45 (66) 24 (67) 21 (67) >  0.999
 Not done 23 (34) 12 (33) 11 (34)
Relapse after primary treatment
 No relapse 29 (43) 18 (50) 11 (34) 0.226
 Relapse 39 (57) 18 (50) 21 (66)
Autologous stem cell transplantation
 Done 12 (18) 7 (19) 5 (16) 0.758
 Not done 56 (82) 29 (81) 27 (84)
Relapse or progression
 None 25 (37) 18 (50) 7 (22) 0.023
 Occurred 43 (63) 18 (50) 25 (78)
Survival status
 Alive 39 (57) 27 (75) 12 (37) 0.003
 Dead 29 (43) 9 (25) 20 (63)