Table 2.
All patients (n = 68) |
Low sPD-L1 (n = 36) |
High sPD-L1 (n = 32) |
|||||
---|---|---|---|---|---|---|---|
n | (%) | n | (%) | n | (%) | P | |
HD-MTX chemotherapy | |||||||
Completed | 61 | (90) | 32 | (89) | 29 | (91) | > 0.999 |
Failed to complete | 7 | (10) | 4 | (11) | 3 | (9) | |
Response to HD-MTX treatment | |||||||
CR/PR | 54/12 | (97) | 30/6 | (100) | 24/6 | (94) | 0.486 |
SD/PD | 1/1 | (3) | 0/0 | (0) | 1/1 | (6) | |
Intrathecal chemotherapy | |||||||
Combined | 26 | (38) | 10 | (28) | 16 | (50) | 0.081 |
Not combined | 42 | (62) | 26 | (72) | 16 | (50) | |
Whole brain radiotherapy | |||||||
Done | 45 | (66) | 24 | (67) | 21 | (67) | > 0.999 |
Not done | 23 | (34) | 12 | (33) | 11 | (34) | |
Relapse after primary treatment | |||||||
No relapse | 29 | (43) | 18 | (50) | 11 | (34) | 0.226 |
Relapse | 39 | (57) | 18 | (50) | 21 | (66) | |
Autologous stem cell transplantation | |||||||
Done | 12 | (18) | 7 | (19) | 5 | (16) | 0.758 |
Not done | 56 | (82) | 29 | (81) | 27 | (84) | |
Relapse or progression | |||||||
None | 25 | (37) | 18 | (50) | 7 | (22) | 0.023 |
Occurred | 43 | (63) | 18 | (50) | 25 | (78) | |
Survival status | |||||||
Alive | 39 | (57) | 27 | (75) | 12 | (37) | 0.003 |
Dead | 29 | (43) | 9 | (25) | 20 | (63) |