Table 2.

Pain models used to evaluate long-term effects of neonatal pain with or without subsequent pain later in life.

1st Stimulus	2nd Stimulus	References
		(165 , 174 , 175 )
		(134, 135, 165, 175–179)
		(58, 180)
		(165, 181–184)
		(57, 59, 62, 177, 184, 185)
		(97, 100, 178, 186–188)
		(189–192)
		(193, 194)
		(195)
		(171)
		(194)
		(135, 145, 196–198)
		(199)
		(61)
		(200)
		(96)
		(201)
		(202)
		(203)
		(37, 98, 204)
		(205)
		(16, 97, 100, 163, 206, 207)
		(144)
		(164, 208, 209)
This illustration represents different pain models used to mimic injury that occurs early in life (P0–17) and/or later in life (P6–125). These models have been used to evaluate the long-term consequences of neonatal pain and inflammation.
key	Complete Freud's Adjuvant (CFA)	Formalin	Incision
	Carrageenan (CAR)	Stress	Nerve Injury
	Capsaicin (CAP)	RNP	Other (e.g. LPS)