Table 4.

Univariate and multivariable analysis for OS incorporating values of Tim-3 and sIL2-Rα dichotomized in two groups.

	OS Univariate			OS Multivariate***
	HR	95% CI	P	HR	95% CI	P
Tim3 over 950 pg/ml	4.699	1.652–13.080	0.003	6.214	1.939–19.910	0.002
REC IL-2 over 8,100 pg/ml	2.762	1.530–4.988	0.0007	2.644	1.308–5.347	0.006
Age	1.034	1.007–1.062	0.01	1.001	0.974–1.028	0.95
Source: Marrow vs. PBSC	2.053	1.142–3.691	0.01	2.328	1.082–5.007	0.03
Diagnosis: MDS/AA/MPN	0.223	0.054–0.920	0.03	0.097	0.013–0.726	0.02
Donor type: MUD-HAPLO vs. HLA-ID SIBLING	1.450	0.814–2.585	0.20	1.100	0.484–2.502	0.82
GVHD prophylaxis: other than CSA + MTX + ATG vs. CSA + MTX + ATG	1.794	1.011–3.184	0.04	2.313	1.030–5.192	0.04
Conditioning regimen FMA vs. RIC	1.038	0.503–2.139	0.92

^***Studied in the set of 75 patients in which both data on TIM-3 and REC IL-2 were available.