. 2020 Feb 11;8:e8499. doi: 10.7717/peerj.8499

Table 2. Univariable and final multivariable models for ESRD in the derivation cohort.

Variable	Univariable		Multivariable
	OR (95% CI)	P	OR (95% CI)	P
Age (per 15-year increase)	1.41 (0.98–2.03)	0.069
Sex (male vs female)	0.97 (0.63–1.48)	0.883
Duration of DM (years)	0.10 (0.97–1.03)	0.987
Duration of hypertension (years)	1.04 (1.01–1.08)	0.024
Pathological grade	1.89 (1.45–2.52)	<0.001	1.43 (1.04–1.98)	0.03
RASB use	0.24 (0.14–0.39)	<0.001
Hb (g/dL)	0.97 (0.96–0.98)	<0.001
CRP (mg/l) PCT (ng/ml)	0.10 (0.99–1.01) 0.94 (0.70–1.02)	0.666 0.392
ESR (mm/l)	1.01 (1.00–1.02)	<0.001
HbA_1c (%)	0.83 (0.75–0.93)	0.001
Alb (g/L)	0.96 (0.93–0.99)	0.003
24hUTP (g)	1.13 (1.07–1.20)	<0.001
Log urinary ACR (mg/g)	1.61 (1.12–2.37)	0.012	1.08 (1.01–1.16)	0.04
TCr (g/g)	1.11 (1.05–1.18)	<0.001
Scr (µmol/l) Urea (mmol/l)	1.02 (1.01–1.03) 1.25 (1.18–1.34)	<0.001 <0.001
Cystatin C (mg/l)	5.77 (3.94–8.88)	<0.001	4.94 (3.34–7.66)	<0.001
TG (mmol/l)	0.96 (0.86–1.06)	0.430
HDL-cholesterol (mmol/l)	0.78 (0.50–1.19)	0.256
LDL-cholesterol (mmol/l)	1.06 (0.93–1.21)	0.390
Serum lipids	0.24 (0.02–2.12)	0.207
eGFR (ml/min/1.73 m²)	0.95 (0.94–0.96)	<0.001	0.97(0.96–0.98)	<0.001
PTH (pg/ml)	1.01 (1.00–1.02)	<0.001
BNP (pg/ml*10³)	1.08 (1.05–1.12)	<0.001	1.05 (1.01–1.10)	0.01
CKmb (ng/ml)	0.98 (0.97–0.99)	0.04

Notes.